Eleutheroside B1

CAS No. 16845-16-2

Eleutheroside B1( —— )

Catalog No. M29245 CAS No. 16845-16-2

Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Eleutheroside B1
  • Note
    Research use only, not for human use.
  • Brief Description
    Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities.
  • Description
    Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities.(In Vitro):eleutheroside B1 may affect N?glycan biosynthesis, the chemokine signaling pathway, cytokine?cytokine receptor interaction and, in particular, may target the POLR2A to inhibit the production of influenza virus genes.
  • In Vitro
    Eeutheroside B1 (100?μg/ml; 24 hours) influences mRNA expression of host genes and virus genes in A549 cells. RT-PCR Cell Line:Virus-infected A549 cells Concentration:100?μg/ml Incubation Time:24 hours Result:The expression of host genes (MAN2A2, POLR2A) and virus genes (PA, PB1, PB2, HA) were decreased.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Influenza Virus
  • Recptor
    Influenza Virus
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    16845-16-2
  • Formula Weight
    384.337
  • Molecular Formula
    C17H20O10
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    COc1cc2ccc(=O)oc2c(OC)c1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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